FEATURES

FAMILY

DESCRIPTION

Also known as HYAS3_HUMAN, HAS3. Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HAS3

Hyaluronan synthase 3

HAS3

Molecular Synopsis