FEATURES

FAMILY

DESCRIPTION

Also known as F16P2_HUMAN, FBP2. Catalyzes the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. Homotetramer. Interacts with ALDOA; the interaction blocks inhibition by physiological concentrations of AMP and reduces inhibition by Ca(2+). Interacts with alpha-actinin and F-actin.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FBP2

Fructose-1, 6-bisphosphatase isozyme 2

Mutations

Mutation(s) distribution

Mutations table

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