FEATURES

FAMILY

DESCRIPTION

Also known as PACN2_CHICK, PACSIN2. Regulates the morphogenesis and endocytosis of caveolae (By similarity). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.

EXTERNAL LINKS

uniprot
enzyme classification

PACSIN2

Protein kinase C and casein kinase substrate in neurons protein 2

PACSIN2

Molecular Synopsis