FEATURES

FAMILY

DESCRIPTION

Also known as DCP2_SCHPO, dcp2. Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body. Component of the decapping complex composed of dcp1 and dcp2 (By similarity). Interacts with edc3.

EXTERNAL LINKS

uniprot
enzyme classification

dcp2

mRNA decapping complex subunit 2

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

dcp2

Structural Ligandability

Domains Chains

Distribution