FEATURES

FAMILY

DESCRIPTION

Also known as DFB4A_HUMAN, DEFB4A, DEFB4B, DEFB102, DEFB2, DEFB4. Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DEFB4A, DEFB4B

Beta-defensin 4A

Mutations

Mutation(s) distribution

Mutations table

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