FEATURES

FAMILY

DESCRIPTION

Also known as NRNA_BACSU, nrnA, ytqI. Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819), and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. Tetramer.

EXTERNAL LINKS

uniprot
enzyme classification

nrnA

Bifunctional oligoribonuclease and PAP phosphatase NrnA

Mutations

Mutation(s) distribution

Mutations table

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