FEATURES

FAMILY

DESCRIPTION

Also known as HPGDS_RAT, Hpgds, Gsts, Pgds, Ptgds2. Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Homodimer.

Also known as HPGDS_RAT, Hpgds, Gsts, Pgds, Ptgds2. Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a ...

EXTERNAL LINKS

uniprot
enzyme classification

Hpgds

Hematopoietic prostaglandin D synthase

Hpgds

Molecular Synopsis