FEATURES

FAMILY

DESCRIPTION

Also known as NUDC_MOUSE, Nudc. Plays a role in neurogenesis and neuronal migration (PubMed:11734602). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (By similarity). Necessary for cytokinesis and cell proliferation (By similarity). Interacts with PLK1 (By similarity). Interacts with PAFAH1B1 (PubMed:9601647). Part of a complex containing PLK1, NUDC, dynein and dynactin (PubMed:11734602). Interacts with DCDC1 (By similarity). Interacts with EML4 (via WD repeats) (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Nudc

Mutations

Mutation(s) distribution

Mutations table