FEATURES

FAMILY

DESCRIPTION

Also known as RB33B_MOUSE, Rab33b. Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation. Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP. Interacts with RGP1 (By similarity). Interacts with ATG16L1; the interaction is important for autophagosome formation (PubMed:18448665). Interacts with ATG16L2; however interaction is approximately hundred times lower than for ATG16L1 (PubMed:22082872).

EXTERNAL LINKS

uniprot
enzyme classification

Rab33b

Mutations

Mutation(s) distribution

Mutations table