FEATURES

DESCRIPTION

Also known as MIS19_SCHPO, mis19, eic1, kis1. Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:24774534, PubMed:24789708, PubMed:25375240). Links mis16 and mis18 to recruit CENP-A through interacting with non-sense-mediated mRNA decay (NMD) factors and the SWI/SNF complex (PubMed:24774534). Links also mis18 with the CCAN/mis6/ctf19 complex to promote CENP-A assembly (PubMed:24789708). Component of the CENP-A recruiting complex composed of at least mis16, mis19, mis19 and mis20 (PubMed:24774534, PubMed:24789708, PubMed:25375240).

EXTERNAL LINKS

uniprot
enzyme classification

mis19

CENP-A recruiting complex protein mis19

mis19

Molecular Synopsis