FEATURES

FAMILY

DESCRIPTION

Also known as NDUS4_HUMAN, NDUFS4. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme. Interacts with BCAP31 and TOMM40; the interaction mediates its translocation to the mitochondria; the interaction with BCAP31 is direct (PubMed:31206022).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NDUFS4

NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

NDUFS4

Molecular Synopsis