FEATURES

FAMILY

DESCRIPTION

Also known as MAAI_HUMAN, GSTZ1, MAAI. Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GSTZ1

Maleylacetoacetate isomerase

GSTZ1

Molecular Synopsis