FEATURES

FAMILY

DESCRIPTION

Also known as AGRB3_HUMAN, ADGRB3, BAI3, KIAA0550. Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1 (PubMed:24567399). Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembrane moiety. Interacts (via TSP N-terminal domains) with C1QL1, C1QL2, C1QL3 and C1QL4 (PubMed:21262840). Interacts with ELMO1, ELMO2 AND ELMO3 (PubMed:24567399).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADGRB3

Mutations

Mutation(s) distribution

Mutations table