FEATURES

FAMILY

DESCRIPTION

Also known as SNF1_SCHPO, ssp2. Serine/threonine protein kinase essential for release from glucose repression via the phosphorylation of scr1 upon glucose deprivation (PubMed:22140232). Catalytic subunit of the AMP-activated protein kinase complex also known as the SNF1 kinase complex (Snf1c), a central regulator of cellular energy homeostasis, which, in response to a fall in intracellular ATP levels, activates energy-producing pathways and inhibits energy-consuming processes (PubMed:22375066). The complex phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, leading to transcriptional activation through TBP recruitment to the promoters (By similarity). Regulates proper cell cycle exit and sexual differentiation (PubMed:22375066). Regulates also ste11 levels under nitrogen deprivation (PubMed:22375066). Component of the AMP-activated protein kinase complex also known as the SNF1 kinase complex (Snf1c), a heterotrimeric complex composed of a catalytic subunit alpha and 2 regulatory subunits beta (amk2) and gamma (cbs2) (PubMed:17289942, PubMed:17937917).

EXTERNAL LINKS

ssp2

Mutations

Mutation(s) distribution

Mutations table