FEATURES

DESCRIPTION

Also known as FCG3B_HUMAN, FCGR3B, CD16B, FCG3, FCGR3, IGFR3. Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. Monomer. Interacts with INPP5D/SHIP1 (By similarity).

Also known as FCG3B_HUMAN, FCGR3B, CD16B, FCG3, FCGR3, IGFR3. Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FCGR3B

Low affinity immunoglobulin gamma Fc region receptor III-B

FCGR3B

Molecular Synopsis