FEATURES

FAMILY

DESCRIPTION

Also known as STK16_HUMAN, STK16, MPSK1, PKL12, TSF1. Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. Monomer. Interacts with DRG1 (via its N-terminal); the interaction phosphorylates DRG1.

Also known as STK16_HUMAN, STK16, MPSK1, PKL12, TSF1. Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. ...

EXTERNAL LINKS

STK16

Serine/threonine-protein kinase 16

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

STK16

Structural Ligandability

Domains Chains

Distribution