FEATURES

FAMILY

DESCRIPTION

Also known as RPN10_SCHPO, rpn10, pus1. Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation. The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively (By similarity). Interacts with uch2.

EXTERNAL LINKS

uniprot
enzyme classification

rpn10

26S proteasome regulatory subunit rpn10

Mutations

Mutation(s) distribution

Mutations table

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