FEATURES

FAMILY

DESCRIPTION

Also known as MAG2_SCHPO, mag2. Alkylbase DNA glycosidase-like protein that shows no DNA glycosylase activity for alkylated bases (PubMed:23273506, PubMed:23245849). The molecular role of mag2 appears to be abasic (AP) site recognition and protection, while possibly facilitating damage signaling by structurally sculpting the DNA substrate (PubMed:18270439, PubMed:23245849). Stimulates AP site binding to mismatch repair protein mutS (PubMed:23245849).

EXTERNAL LINKS

uniprot
enzyme classification

mag2

Alkylbase DNA glycosidase-like protein mag2

mag2

Molecular Synopsis