FEATURES

FAMILY

DESCRIPTION

Also known as CPSF4_HUMAN, CPSF4, CPSF30, NAR, NEB1. Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with FIP1L1.

Also known as CPSF4_HUMAN, CPSF4, CPSF30, NAR, NEB1. Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CPSF4

Mutations

Mutation(s) distribution

Mutations table