FEATURES

FAMILY

DESCRIPTION

Also known as OXDA_PIG, DAO. Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

DAO

Mutations

Mutation(s) distribution

Mutations table