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FEATURES

FAMILY

multicopper oxidase family

DESCRIPTION

Also known as FA8_HUMAN, F8, F8C. Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa. Interacts with VWF/vWF. vWF binding is essential for the stabilization of F8 in circulation.

Also known as FA8_HUMAN, F8, F8C. Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa. Interacts ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

F8

Coagulation factor VIII

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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