FEATURES

FAMILY

DESCRIPTION

Also known as F13A_HUMAN, F13A1, F13A. Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Tetramer of two A chains (F13A1) and two B (F13B) chains.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

F13A1

Coagulation factor XIII A chain

Mutations

Mutation(s) distribution

Mutations table

Search Mutation