FEATURES

FAMILY

DESCRIPTION

Also known as PA2A1_NAJAT, PA2A1. Snake venom phospholipase A2 (PLA2) that has high affinity for muscarinic acetylcholine receptors mAChRs (CHRM) and has the ability to activate them. In guinea-pig ileum, produces an onset and dose-dependent contraction. Has also weak anticoagulant activity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

PA2A1

Acidic phospholipase A2 1

PA2A1

Molecular Synopsis