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FEATURES

FAMILY

peptidase S1 family

DESCRIPTION

Also known as CFAD_HUMAN, CFD, DF, PFD. Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

Also known as CFAD_HUMAN, CFD, DF, PFD. Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CFD

Complement factor D

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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