FEATURES

FAMILY

DESCRIPTION

Also known as NEU1_HUMAN, OXT, OT. Neurophysin 1 specifically binds oxytocin., Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) (PubMed:18174156). Interacts with oxytocin receptor (Ki=1.5 nM) (PubMed:18174156). Interacts with vasopressin V1aR/AVPR1A (Ki=37 nM), V1bR/AVPR1B (Ki=222 nM) and V2R/AVPR2 receptors (Ki=823 nM) (PubMed:18174156).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OXT

Oxytocin-neurophysin 1

OXT

Molecular Synopsis