FEATURES

DESCRIPTION

Also known as IL2RA_HUMAN, IL2RA. Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

IL2RA

Mutations

Mutation(s) distribution

Mutations table