FEATURES

FAMILY

DESCRIPTION

Also known as MYO4_CAEEL, unc-54, myo-4. Required for muscle contraction. Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Forms a complex composed of chaperone unc-45, unc-54 and ubiquitin-protein ligase ufd-2; promotes poly-ubiquitination of unfolded unc-54 (PubMed:29396393). Within the complex interacts with unc-45 (via UCS domain) and ufd-2 (PubMed:29396393). Interacts with itr-1 (via c-terminal coiled coil domain) (PubMed:12062062).

EXTERNAL LINKS

uniprot
enzyme classification

unc-54

Myosin-4

unc-54

Molecular Synopsis