FEATURES

FAMILY

DESCRIPTION

Also known as SCE1_YEAST, SCEI, OMEGA, SECY. Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the 21S rRNA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Specifically recognizes and cleaves the sequence 5'-TAGGGATAACAGGGTAAT-3'. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

SCEI

Intron-encoded endonuclease I-SceI

SCEI

Molecular Synopsis