FEATURES

FAMILY

DESCRIPTION

Also known as MMP1_HUMAN, MMP1, CLG. Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369). (Microbial infection) Interacts with HIV-1 Tat.

Also known as MMP1_HUMAN, MMP1, CLG. Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMe ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MMP1

Interstitial collagenase

MMP1

Molecular Synopsis