FEATURES

FAMILY

DESCRIPTION

Also known as OTC1_ECOLI, argI. Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. In E.coli strain K12, trimer of identical or non-identical chains are composed of ArgI (I) and/or ArgF (F) (PubMed:6369246, PubMed:4558857, PubMed:789338). The trimer has the following composition: FFI, FFF, FII, III (PubMed:6369246, PubMed:4558857, PubMed:789338). E.coli strains B and W, which are known to contain only ArgI, produce only a trimer of identical chains (III).

EXTERNAL LINKS

uniprot
enzyme classification

argI

Ornithine carbamoyltransferase subunit I

argI

Molecular Synopsis