FEATURES

FAMILY

DESCRIPTION

Also known as PILA_PSEAE, pilA, fimA. Major component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers (PubMed:9282737, PubMed:26041805, PubMed:31431558). In addition, plays a critical role in type II secretion of exoenzymes by interacting with specific components such as XcpT or XcpU (PubMed:9282737). Modulates host calcium signaling through interaction with host calcium-modulating cyclophilin ligand (PubMed:23266901). Interacts with PilJ (PubMed:26041805). Interacts with PilS at the inner membrane (PubMed:27162347). Interacts with type II secretion system (T2SS) components XcpT, XcpU and XcpW (PubMed:9282737).

Also known as PILA_PSEAE, pilA, fimA. Major component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, ...

EXTERNAL LINKS

pilA

Type IV major pilin protein PilA

pilA

Molecular Synopsis