FEATURES

FAMILY

DESCRIPTION

Also known as PERM_HUMAN, MPO. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MPO

Myeloperoxidase

MPO

Molecular Synopsis