FEATURES

DESCRIPTION

Also known as LA_HUMAN, SSB. Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597). Interacts with DDX15. May interact with RUFY1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SSB

Lupus La protein

SSB

Molecular Synopsis