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FEATURES

FAMILY

type II topoisomerase family

DESCRIPTION

Also known as TOP2_YEAST, TOP2, TOR3. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. Homodimer.

Also known as TOP2_YEAST, TOP2, TOR3. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential durin ...

EXTERNAL LINKS

uniprot
enzyme classification

TOP2

DNA topoisomerase 2

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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