FEATURES

DESCRIPTION

Also known as GP1BA_HUMAN, GP1BA. GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage (PubMed:17008541, PubMed:2070794). Interacts with FLNB (PubMed:9651345). Interacts with FLNA (via filamin repeats 4, 9, 12, 17, 19, 21, and 23) (PubMed:19828450).

Also known as GP1BA_HUMAN, GP1BA. GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GP1BA

Platelet glycoprotein Ib alpha chain

Structural Ligandability

Domains Chains

0 chains assessed

12 chains not associated with a domain

GP1BA

Structural Ligandability

Domains Chains

Distribution