FEATURES

FAMILY

DESCRIPTION

Also known as METAS_ECOLI, metAS, metA. Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine (PubMed:10572016, PubMed:17442255, PubMed:17302437, PubMed:28581482). Utilizes a ping-pong kinetic mechanism in which the succinyl group of succinyl-CoA is initially transferred to the enzyme to form a succinyl-enzyme intermediate before subsequent transfer to homoserine to form the final product, O-succinylhomoserine (PubMed:10572016, PubMed:17442255, PubMed:17302437). Cannot use acetyl-CoA (PubMed:10572016). Homodimer.

Also known as METAS_ECOLI, metAS, metA. Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine (PubMed:10572016, PubMed:17442255, PubMed:17302437, PubMed:285 ...

EXTERNAL LINKS

uniprot
enzyme classification

metAS

Homoserine O-succinyltransferase

metAS

Molecular Synopsis