FEATURES

FAMILY

glycosyl hydrolase 6 (cellulase B) family

DESCRIPTION

Also known as GUX2_HYPJE, cbh2. Exocellobiohydrolases (CBH) that catalyzes the hydrolysis of 1, 4-beta-D-glucosidic bonds in cellulose to release the disaccharide cellobiose (Ref.3). The degradation of cellulose involves an interplay between different cellulolytic enzymes. Hydrolysis starts with endoglucanases (EGs), which cut internal beta-1, 4-glucosidic bonds in cellulose to reduce the polymerization degree of the substrate and create new chain ends for exocellobiohydrolases (CBHs). The CBHs release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain. Finally, beta-1, 4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units (Probable).

EXTERNAL LINKS

cbh2

Mutations

Mutation(s) distribution

Mutations table