FEATURES

FAMILY

DESCRIPTION

Also known as RHOC_HUMAN, RHOC, ARH9, ARHC. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. Interacts with RTKN (By similarity). Interacts with AKAP13 (PubMed:11546812). Interacts with DIAPH1 (PubMed:15864301). Interacts with PKN2 (PubMed:20974804). Interacts with ROCK1 and ROCK2 (PubMed:8816443). Interacts with ARHGDIA (PubMed:20400958). Interacts with RIPOR1 (PubMed:27807006).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RHOC

Rho-related GTP-binding protein RhoC

RHOC

Molecular Synopsis