FEATURES

FAMILY

DESCRIPTION

Also known as NFL_MOUSE, Nefl, Nf68, Nfl. Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (PubMed:22723690). Forms homodimers (in vitro) (By similarity). Forms heterodimers with NEFH or NEFM; which can further hetero-oligomerize (in vitro) (By similarity). Forms heterodimers with INA (in vitro) (By similarity). Interacts with ARHGEF28. Interacts with TRIM2.

Also known as NFL_MOUSE, Nefl, Nf68, Nfl. Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May ...

EXTERNAL LINKS

uniprot
enzyme classification

Nefl

Neurofilament light polypeptide

Nefl

Structural Ligandability

Domains Chains

Distribution