FEATURES

FAMILY

DESCRIPTION

Also known as SCTG_SHIFL, mxiM, sctG. Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:10085046, PubMed:11717255). Pilot protein that is required for the proper localization of the secretin MxiD/SctC in the outer membrane (PubMed:11717255). Also influences both MxiD/SctC multimerization and stability (PubMed:11717255). Required for both Ipa translocation and tissue culture cell invasion (PubMed:10085046). Binds lipids (PubMed:15775974). Monomer (PubMed:15775974). Interacts with the secretin MxiD/SctC (PubMed:11717255, PubMed:15775974, PubMed:18940609).

EXTERNAL LINKS

mxiM

Mutations

Mutation(s) distribution

Mutations table