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FEATURES

FAMILY

DESCRIPTION

Also known as NCZS_STRCZ, ncsA. NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors). NCS binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.

Also known as NCZS_STRCZ, ncsA. NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors). NCS binds non-covalently to a chromophore which is the cyto ...

EXTERNAL LINKS

uniprot
enzyme classification

ncsA

Neocarzinostatin

Molecular Synopsis

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