FEATURES

FAMILY

DESCRIPTION

Also known as COAD_ECOLI, coaD, kdtB, yicA. Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (PubMed:10480925, PubMed:17873050). CoA is not a substrate for the enzyme (PubMed:10480925). Homohexamer, a dimerized trimer with a solvent channel through the middle (PubMed:10480925, PubMed:10205156, PubMed:11812124, PubMed:12837781, PubMed:17873050). In crystals only 1 trimer is seen to bind substrate/product at a time (PubMed:10205156, PubMed:11812124).

Also known as COAD_ECOLI, coaD, kdtB, yicA. Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (PubMed:10480925, PubMed:178 ...

EXTERNAL LINKS

uniprot
enzyme classification

coaD

Phosphopantetheine adenylyltransferase

coaD

Molecular Synopsis