FEATURES

FAMILY

DESCRIPTION

Also known as PA1_ECOLI, pldA. Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins. Homodimer; dimerization is reversible, and the dimeric form is the active one.

EXTERNAL LINKS

uniprot
enzyme classification

pldA

Phospholipase A1

pldA

Molecular Synopsis