FEATURES

FAMILY

DESCRIPTION

Also known as DEAD_ECOLI, deaD, csdA, mssB, rhlD. DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity at low temperature. Involved in 50S ribosomal subunit assembly, acting after SrmB, and could also play a role in the biogenesis of the 30S ribosomal subunit. In addition, is involved in mRNA decay, via formation of a cold-shock degradosome with RNase E. Also stimulates translation of some mRNAs, probably at the level of initiation. Interacts with the 50S ribosomal subunit upon shifting to 15 degrees Celsius. Also found associated with the RNA degradosome at 15 degrees Celsius; binds RNase E (rne).

Also known as DEAD_ECOLI, deaD, csdA, mssB, rhlD. DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation ...

EXTERNAL LINKS

deaD

ATP-dependent RNA helicase DeaD

deaD

Molecular Synopsis