FEATURES

FAMILY

DESCRIPTION

Also known as KDGL_ECOLI, dgkA, dgk. Catalyzes the ATP-dependent phosphorylation of sn-l, 2-diacylglycerol (DAG) to phosphatidic acid (PubMed:218816, PubMed:6277376, PubMed:6303781, PubMed:2984194, PubMed:3009449, PubMed:2828054, PubMed:9305868). Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis (PubMed:217867, PubMed:6305970). In vitro, phosphorylates various substrates, including sn-1, 2-dioleoylglycerol, sn-1, 2-dioctanoylglycerol, sn-1, 2-dipalmitoylglycerol, sn-1, 2-dipalmitate and ceramide (PubMed:218816, PubMed:2984194, PubMed:3009449, PubMed:3021764, PubMed:2828054). Catalyzes direct phosphoryl transfer from Mg-ATP to diacylglycerol and does not form an enzyme-phosphate intermediate (PubMed:9305868). Homotrimer.

Also known as KDGL_ECOLI, dgkA, dgk. Catalyzes the ATP-dependent phosphorylation of sn-l, 2-diacylglycerol (DAG) to phosphatidic acid (PubMed:218816, PubMed:6277376, PubMed:6303781, PubMed:298419 ...

EXTERNAL LINKS

dgkA

Diacylglycerol kinase

dgkA

Molecular Synopsis