FEATURES

FAMILY

DESCRIPTION

Also known as INGK_ECOLI, gsk. Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively (PubMed:7721718, PubMed:7665468, PubMed:10879466). Can also use deoxyguanosine and xanthosine, but not adenosine, uridine, cytidine or deoxythymidine (PubMed:7665468, PubMed:10879466). Shows a strong preference for guanosine (PubMed:7665468, PubMed:10879466). dATP can serve as a phosphate donor as well as ATP. Shows weaker activity with UTP and CTP (PubMed:7665468, PubMed:10879466). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

gsk

Mutations

Mutation(s) distribution

Mutations table