FEATURES

FAMILY

DESCRIPTION

Also known as PSPA_ECOLI, pspA. The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity, efficient translocation and maintenance of the proton motive force. Exists in at least two different oligomeric assemblies. Regulatory function involves the formation of a complex with PspF, which is composed of around 6 PspF subunits and 6 PspA subunits. Maintenance of membrane integrity involves the formation of a 36-mer ring complex. Interacts with PspB and PspC.

EXTERNAL LINKS

pspA

Phage shock protein A

pspA

Molecular Synopsis