FEATURES

FAMILY

DESCRIPTION

Also known as GLYCO_MOKV, G. Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity). Homotrimer. Interacts with matrix protein (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

G

Mutations

Mutation(s) distribution

Mutations table