FEATURES

FAMILY

DESCRIPTION

Also known as NANH_VIBCH, nanH. Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections. Facilitates cholera toxin binding to host intestinal epithelial cells by converting cell surface polysialogangliosides to GM1 monogangliosides. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

nanH

Sialidase

nanH

Molecular Synopsis