FEATURES

FAMILY

DESCRIPTION

Also known as GP42_EBVG, BZLF2. Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells (By similarity). Forms a complex with gp25 and gp85 via its N-terminus; this complex is used for invasion of B-lymphocytes.

EXTERNAL LINKS

uniprot
enzyme classification

BZLF2

Glycoprotein 42

BZLF2

Molecular Synopsis